
張昱
職 稱: 研究員
性 別: 女
電 話: 62919883
學(xué) 歷: 博士研究生
Email: zhangyu@rcees.ac.cn
簡(jiǎn)歷:
張昱,中國(guó)科學(xué)院生態(tài)環(huán)境研究中心研究員,現(xiàn)任環(huán)境水質(zhì)學(xué)國(guó)家重點(diǎn)實(shí)驗(yàn)室副主任。主要從事水環(huán)境微生物風(fēng)險(xiǎn)識(shí)別與控制研究,近年來在環(huán)境微生物耐藥性傳播與阻斷研究方面取得創(chuàng)新成果,應(yīng)用于行業(yè)工程示范和環(huán)境管理。獲國(guó)家自然科學(xué)二等獎(jiǎng)、國(guó)家科技進(jìn)步二等獎(jiǎng)、中國(guó)科學(xué)院杰出成就獎(jiǎng)(集體)、朱李月華優(yōu)秀教師等獎(jiǎng)勵(lì)。入選WHO抗微生物藥物耐藥性戰(zhàn)略和技術(shù)專家組,任中國(guó)生態(tài)學(xué)學(xué)會(huì)理事及微生物生態(tài)專委會(huì)主任、中國(guó)制藥企業(yè)管理協(xié)會(huì)EHS技術(shù)專家等。
研究方向:
水環(huán)境微生物風(fēng)險(xiǎn)識(shí)別與控制研究
招生方向:
水環(huán)境微生物風(fēng)險(xiǎn)識(shí)別與控制研究,歡迎環(huán)境科學(xué)與工程,環(huán)境微生物、分析化學(xué)、化學(xué)工程等專業(yè)學(xué)生報(bào)考.
專家類別:
高級(jí)
社會(huì)任職:
World Health Organization(WHO) 抗微生物藥物耐藥性戰(zhàn)略和技術(shù)咨詢組專家
中國(guó)生態(tài)學(xué)學(xué)會(huì)理事及微生物生態(tài)專業(yè)委員會(huì)主任委員
期刊One health advance 編委
期刊Water Conservation Science and Engineering 編委
中國(guó)生態(tài)學(xué)學(xué)會(huì)理事及微生物生態(tài)專業(yè)委員會(huì)主任委員
期刊One health advance 編委
期刊Water Conservation Science and Engineering 編委
獲獎(jiǎng)及榮譽(yù):
張昱(主要完成者),飲用水水質(zhì)風(fēng)險(xiǎn)識(shí)別與控制研究集體,中國(guó)科學(xué)院杰出科技成就獎(jiǎng),2021
張昱(4/15),城市污水處理系統(tǒng)運(yùn)行特性與調(diào)控機(jī)制,華夏建設(shè)科學(xué)技術(shù)獎(jiǎng)一等獎(jiǎng),2020
張昱(2/5),飲用水中天然源風(fēng)險(xiǎn)物質(zhì)的識(shí)別、轉(zhuǎn)化與調(diào)控機(jī)制,國(guó)家自然科學(xué)二等獎(jiǎng), 2017
張昱(2/6),基于物質(zhì)形態(tài)原位調(diào)控的難降解有機(jī)廢水低耗處理與資源化技術(shù),中國(guó)石油和化學(xué)工業(yè)聯(lián)合會(huì)技術(shù)發(fā)明獎(jiǎng),2016
北京市科技新星計(jì)劃A類,2008
張昱(7/8),飲用水質(zhì)安全風(fēng)險(xiǎn)的末端控制技術(shù)與應(yīng)用,科技進(jìn)步,國(guó)家二等獎(jiǎng),2007
張昱(4/15),城市污水處理系統(tǒng)運(yùn)行特性與調(diào)控機(jī)制,華夏建設(shè)科學(xué)技術(shù)獎(jiǎng)一等獎(jiǎng),2020
張昱(2/5),飲用水中天然源風(fēng)險(xiǎn)物質(zhì)的識(shí)別、轉(zhuǎn)化與調(diào)控機(jī)制,國(guó)家自然科學(xué)二等獎(jiǎng), 2017
張昱(2/6),基于物質(zhì)形態(tài)原位調(diào)控的難降解有機(jī)廢水低耗處理與資源化技術(shù),中國(guó)石油和化學(xué)工業(yè)聯(lián)合會(huì)技術(shù)發(fā)明獎(jiǎng),2016
北京市科技新星計(jì)劃A類,2008
張昱(7/8),飲用水質(zhì)安全風(fēng)險(xiǎn)的末端控制技術(shù)與應(yīng)用,科技進(jìn)步,國(guó)家二等獎(jiǎng),2007
承擔(dān)科研項(xiàng)目情況:
國(guó)家重點(diǎn)研發(fā)計(jì)劃,長(zhǎng)江黃河流域飲用水病原微生物數(shù)據(jù)庫構(gòu)建及風(fēng)險(xiǎn)管控技術(shù),2022YFC3204700,2022-11-2026-10,2443萬,在研,項(xiàng)目負(fù)責(zé)人
國(guó)家自然科學(xué)基金委員會(huì),生命學(xué)部專項(xiàng)項(xiàng)目,32141002,重要耐藥菌/耐藥基因在“動(dòng)物-環(huán)境-人群”鏈條中的傳播機(jī)制和風(fēng)險(xiǎn)研究,2022-1-2025-12,280萬,在研, 任務(wù)三負(fù)責(zé)
國(guó)家自然科學(xué)基金委員會(huì),面上項(xiàng)目,22076203,新型四環(huán)素類藥物替加環(huán)素的環(huán)境細(xì)菌耐藥特征及其產(chǎn)生機(jī)制研究,2021-01至2024-12,63萬,在研, 主持
制藥行業(yè),制藥企業(yè)技術(shù)服務(wù),抗生素發(fā)酵菌渣(廢水)無害化處理與資源化利用技術(shù)研發(fā),2019-5至-2021-4, 212萬元,結(jié)題,主持
國(guó)家自然科學(xué)基金委員會(huì),國(guó)際(地區(qū))合作與交流項(xiàng)目(中英)子課題,81861138051,腸桿菌科細(xì)菌廣泛耐藥株/耐藥基因在動(dòng)物相關(guān)環(huán)境的傳播與消減,2019-01至2022-12,40萬人民幣,結(jié)題,子課題主持
英國(guó)Cardiff(卡迪夫) 大學(xué), Determining the clinical and environmental impact, burden and cost of Extensively Drug Resistant Enterobacteriaceae in China HUB,2019-01至2022-12,13萬英鎊, 結(jié)題,主持
中國(guó)科學(xué)院,科技服務(wù)網(wǎng)絡(luò)計(jì)劃項(xiàng)目(STS計(jì)劃):制藥廢水的強(qiáng)化水解預(yù)處理技術(shù)工程化示范,2019-01至2019-12,40萬,結(jié)題,主持
國(guó)家科技重大專項(xiàng)水專項(xiàng)子課題:城市污水難去除和新興微量污染物特征及去除途徑研究,2017-2020,結(jié)題,主持
國(guó)家自然基金重點(diǎn)項(xiàng)目,制藥行業(yè)抗生素與抗藥基因的排放特征、環(huán)境行為及控制技術(shù),2015-2019,結(jié)題,子課題主持
中科院-法國(guó)TOTAL公司國(guó)際合作項(xiàng)目,Biodegradation solution for the viscosified water management, 2014-2015, 結(jié)題,技術(shù)負(fù)責(zé)人
國(guó)家自然基金面上項(xiàng)目,抗生素廢水處理剩余污泥中抗藥基因在環(huán)境中的水平轉(zhuǎn)移分子機(jī)制及調(diào)控原理研究,2013-2016,結(jié)題,主持
國(guó)家自然基金面上項(xiàng)目,抗生素殘留效價(jià)在廢水生物處理系統(tǒng)中的微生物生態(tài)效應(yīng)與調(diào)控原理研究,2012-2015,結(jié)題,主持
國(guó)家科技重大專項(xiàng)水專項(xiàng)子課題:微量有害污染物在城市污水處理過程中的遷移轉(zhuǎn)化規(guī)律研究,2012-2016,結(jié)題,主持
科技部國(guó)際合作子課題:水體中抗生素抗藥菌和抗藥基因的高效控制技術(shù)研究,2013-2016,結(jié)題,主持
中科院-日本學(xué)術(shù)振興會(huì)國(guó)際合作課題,強(qiáng)化厭氧組合新工藝處理抗生素廢水,2012 -2015,結(jié)題,主持
國(guó)家自然基金面上項(xiàng)目,抗生素高脅迫條件下抗藥基因的形成、傳播和控制研究,2009-2011,結(jié)題,主持
國(guó)家科技重大專項(xiàng)水專項(xiàng)課題,城市污水再生利用及水質(zhì)安全保障技術(shù)開發(fā)與工程示范,2008-2011,主持
科技部863探索課題:2007AA06Z319,復(fù)合包覆型鋁基稀土氧化物高效除氟劑開發(fā)及應(yīng)用研究,2007.12-2010.12,主持
國(guó)家自然基金面上項(xiàng)目,基于降解基因信息的壬基酚聚氧乙烯醚降解機(jī)制研究,2006-2008,主持
科技部863青年課題:2004AA649280,用于垃圾滲濾液中高氨氮去除的循環(huán)式MAP工藝研究,2004-2006,主持
國(guó)家自然基金青年項(xiàng)目,金屬氧化物配位羥基對(duì)水體有害陰離子的作用機(jī)制研究,2003-2005,主持
國(guó)家自然科學(xué)基金委員會(huì),生命學(xué)部專項(xiàng)項(xiàng)目,32141002,重要耐藥菌/耐藥基因在“動(dòng)物-環(huán)境-人群”鏈條中的傳播機(jī)制和風(fēng)險(xiǎn)研究,2022-1-2025-12,280萬,在研, 任務(wù)三負(fù)責(zé)
國(guó)家自然科學(xué)基金委員會(huì),面上項(xiàng)目,22076203,新型四環(huán)素類藥物替加環(huán)素的環(huán)境細(xì)菌耐藥特征及其產(chǎn)生機(jī)制研究,2021-01至2024-12,63萬,在研, 主持
制藥行業(yè),制藥企業(yè)技術(shù)服務(wù),抗生素發(fā)酵菌渣(廢水)無害化處理與資源化利用技術(shù)研發(fā),2019-5至-2021-4, 212萬元,結(jié)題,主持
國(guó)家自然科學(xué)基金委員會(huì),國(guó)際(地區(qū))合作與交流項(xiàng)目(中英)子課題,81861138051,腸桿菌科細(xì)菌廣泛耐藥株/耐藥基因在動(dòng)物相關(guān)環(huán)境的傳播與消減,2019-01至2022-12,40萬人民幣,結(jié)題,子課題主持
英國(guó)Cardiff(卡迪夫) 大學(xué), Determining the clinical and environmental impact, burden and cost of Extensively Drug Resistant Enterobacteriaceae in China HUB,2019-01至2022-12,13萬英鎊, 結(jié)題,主持
中國(guó)科學(xué)院,科技服務(wù)網(wǎng)絡(luò)計(jì)劃項(xiàng)目(STS計(jì)劃):制藥廢水的強(qiáng)化水解預(yù)處理技術(shù)工程化示范,2019-01至2019-12,40萬,結(jié)題,主持
國(guó)家科技重大專項(xiàng)水專項(xiàng)子課題:城市污水難去除和新興微量污染物特征及去除途徑研究,2017-2020,結(jié)題,主持
國(guó)家自然基金重點(diǎn)項(xiàng)目,制藥行業(yè)抗生素與抗藥基因的排放特征、環(huán)境行為及控制技術(shù),2015-2019,結(jié)題,子課題主持
中科院-法國(guó)TOTAL公司國(guó)際合作項(xiàng)目,Biodegradation solution for the viscosified water management, 2014-2015, 結(jié)題,技術(shù)負(fù)責(zé)人
國(guó)家自然基金面上項(xiàng)目,抗生素廢水處理剩余污泥中抗藥基因在環(huán)境中的水平轉(zhuǎn)移分子機(jī)制及調(diào)控原理研究,2013-2016,結(jié)題,主持
國(guó)家自然基金面上項(xiàng)目,抗生素殘留效價(jià)在廢水生物處理系統(tǒng)中的微生物生態(tài)效應(yīng)與調(diào)控原理研究,2012-2015,結(jié)題,主持
國(guó)家科技重大專項(xiàng)水專項(xiàng)子課題:微量有害污染物在城市污水處理過程中的遷移轉(zhuǎn)化規(guī)律研究,2012-2016,結(jié)題,主持
科技部國(guó)際合作子課題:水體中抗生素抗藥菌和抗藥基因的高效控制技術(shù)研究,2013-2016,結(jié)題,主持
中科院-日本學(xué)術(shù)振興會(huì)國(guó)際合作課題,強(qiáng)化厭氧組合新工藝處理抗生素廢水,2012 -2015,結(jié)題,主持
國(guó)家自然基金面上項(xiàng)目,抗生素高脅迫條件下抗藥基因的形成、傳播和控制研究,2009-2011,結(jié)題,主持
國(guó)家科技重大專項(xiàng)水專項(xiàng)課題,城市污水再生利用及水質(zhì)安全保障技術(shù)開發(fā)與工程示范,2008-2011,主持
科技部863探索課題:2007AA06Z319,復(fù)合包覆型鋁基稀土氧化物高效除氟劑開發(fā)及應(yīng)用研究,2007.12-2010.12,主持
國(guó)家自然基金面上項(xiàng)目,基于降解基因信息的壬基酚聚氧乙烯醚降解機(jī)制研究,2006-2008,主持
科技部863青年課題:2004AA649280,用于垃圾滲濾液中高氨氮去除的循環(huán)式MAP工藝研究,2004-2006,主持
國(guó)家自然基金青年項(xiàng)目,金屬氧化物配位羥基對(duì)水體有害陰離子的作用機(jī)制研究,2003-2005,主持
代表論著:
Yu Zhang, Jianping Xie, Miaomiao Liu, Zhe Tian, Zhili He, Joy D. van Nostrand, LirenRen, Jizhong Zhou, Min Yang*. Microbial community functional structure in response to antibiotics in pharmaceutical wastewater treatment systems. Water Research. 2013,47:6298-6308.
Miaomiao Liu, Ran Ding, Yu Zhang*, Yingxin Gao, Zhe Tian, Tong Zhang, Min Yang. Abundance and distribution of Macrolide-Lincosamide-Streptogramin resistance genes in ananaerobic-aerobic system treating spiramycin production wastewater. Water Research, 2014, 63:33-41.
Yu Zhang*, Zhe Tian, Miaomiao Liu, Zhou Jason Shi, Lauren Hale, Jizhong Zhou, Min Yang*. High Concentrations of the Antibiotic Spiramycin in Wastewater Lead to High Abundance of Ammonia-Oxidizing Archaea in Nitrifying Populations. Environmental Science and Technology, 2015, 49 (15), 9124–9132.
Zhe Tian, Yu Zhang*, Yuyou Li,Yongzhi Chi , Min Yang. Rapid establishment of thermophilic anaerobic microbial community during the one-step startup of thermophilic anaerobic digestion from a mesophilic digester. Water Research, 2015,69:9-19.
Zhe Tian, Yu Zhang*, Bo Yu, Min Yang. Changes of resistome, mobilome and potential hosts of antibiotic resistance genes during the transformation of anaerobic digestion from mesophilic to thermophilic. Water Research, 2016, 98: 261-269.
Hongrui Chen, Hui Peng, Min Yang, Jianying Hu, Yu Zhang*. Detection, Occurrence, and Fate of Fluorotelomer Alcohols in Municipal Wastewater Treatment Plants. Environmental Science Technology, 2017, 51, 8953?8961.
Qizhen Yi, Yu Zhang*, Yingxin Gao, Zhe Tian, Min Yang. Treatment of Antibiotic Production Wastewater Pretreated with Enhanced Hydrolysis: Simultaneous Reduction of COD and ARGs. Water Research, 2017, 110:211-217.
Dev Raj Joshi , Yu Zhang*, Yinxin Gao, Yuan Liu, Min Yang. Biotransformation of nitrogen- and sulfur-containing pollutants during coking wastewater treatment: Correspondence of performance to microbial community functional structure. Water Research, 2017,121: 338-348.
Ziming Han, Yu Zhang*, Wei An, Junying Lu, Jianying Hu, Min Yang*. Antibiotic resistomes in drinking water sources across a large geographical scale: Multiple drivers and co-occurrence with opportunistic bacterial pathogens. Water Research ,2020,183,116088.
世界衛(wèi)生組織(WHO) 技術(shù)導(dǎo)則“Technical brief on water, sanitation, hygiene and wastewater management to prevent infections and reduce the spread of antimicrobial resistance”領(lǐng)域責(zé)任編制專家,2020年
Miaomiao Liu, Ran Ding, Yu Zhang*, Yingxin Gao, Zhe Tian, Tong Zhang, Min Yang. Abundance and distribution of Macrolide-Lincosamide-Streptogramin resistance genes in ananaerobic-aerobic system treating spiramycin production wastewater. Water Research, 2014, 63:33-41.
Yu Zhang*, Zhe Tian, Miaomiao Liu, Zhou Jason Shi, Lauren Hale, Jizhong Zhou, Min Yang*. High Concentrations of the Antibiotic Spiramycin in Wastewater Lead to High Abundance of Ammonia-Oxidizing Archaea in Nitrifying Populations. Environmental Science and Technology, 2015, 49 (15), 9124–9132.
Zhe Tian, Yu Zhang*, Yuyou Li,Yongzhi Chi , Min Yang. Rapid establishment of thermophilic anaerobic microbial community during the one-step startup of thermophilic anaerobic digestion from a mesophilic digester. Water Research, 2015,69:9-19.
Zhe Tian, Yu Zhang*, Bo Yu, Min Yang. Changes of resistome, mobilome and potential hosts of antibiotic resistance genes during the transformation of anaerobic digestion from mesophilic to thermophilic. Water Research, 2016, 98: 261-269.
Hongrui Chen, Hui Peng, Min Yang, Jianying Hu, Yu Zhang*. Detection, Occurrence, and Fate of Fluorotelomer Alcohols in Municipal Wastewater Treatment Plants. Environmental Science Technology, 2017, 51, 8953?8961.
Qizhen Yi, Yu Zhang*, Yingxin Gao, Zhe Tian, Min Yang. Treatment of Antibiotic Production Wastewater Pretreated with Enhanced Hydrolysis: Simultaneous Reduction of COD and ARGs. Water Research, 2017, 110:211-217.
Dev Raj Joshi , Yu Zhang*, Yinxin Gao, Yuan Liu, Min Yang. Biotransformation of nitrogen- and sulfur-containing pollutants during coking wastewater treatment: Correspondence of performance to microbial community functional structure. Water Research, 2017,121: 338-348.
Ziming Han, Yu Zhang*, Wei An, Junying Lu, Jianying Hu, Min Yang*. Antibiotic resistomes in drinking water sources across a large geographical scale: Multiple drivers and co-occurrence with opportunistic bacterial pathogens. Water Research ,2020,183,116088.
世界衛(wèi)生組織(WHO) 技術(shù)導(dǎo)則“Technical brief on water, sanitation, hygiene and wastewater management to prevent infections and reduce the spread of antimicrobial resistance”領(lǐng)域責(zé)任編制專家,2020年